Description

(2R,2'R)-(-)-[N,N'-Bis(2-Pyridylmethyl]-2,2'-Bipyrrolidinebis(Acetonitrile)Iron(II) Hexafluoroantimonate (Fe(R,R-Pdp) White-Chen Catalyst) is a highly specialized, chiral iron complex designed for asymmetric catalysis. This compound matters because it serves as a powerful and selective catalyst for critical carbon-carbon and carbon-heteroatom bond-forming reactions, enabling the synthesis of enantiomerically pure molecules. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for developing advanced intermediates and active pharmaceutical ingredients (APIs) with high stereochemical fidelity.

Application

• Asymmetric C-H Functionalization: A key catalyst for enantioselective activation of inert C-H bonds, a transformative methodology in synthetic chemistry.
• Pharmaceutical Intermediate Synthesis: Enables the construction of complex, chiral scaffolds found in drug candidates for oncology, CNS disorders, and infectious diseases.
• Asymmetric Oxidation & Hydroxylation: Used in stereoselective oxidation reactions to introduce oxygen functionalities with high enantiomeric excess.
• Methodology Development in Academia: Employed by research institutions for developing new catalytic asymmetric transformations.
• Fine Chemical and Agrochemical Production: Applicable in the synthesis of enantiopure flavors, fragrances, and advanced agrochemical intermediates.
• Ligand Screening and Catalyst Optimization: Serves as a benchmark or precursor in studies aimed at developing next-generation iron catalysts.

Basic Information

Product Name	(2R,2'R)-(-)-[N,N'-Bis(2-Pyridylmethyl]-2,2'-Bipyrrolidinebis(Acetonitrile)Iron(II) Hexafluoroantimonate (Fe(R,R-Pdp) White-Chen Catalyst)
CAS No.	1361315-26-5
Molecular Formula	C₂₈H₃₂F₆FeN₆Sb
Molecular Weight	757.21 g/mol
Synonyms	Fe(R,R-Pdp)(SbF₆)₂; White-Chen Iron Catalyst; (R,R)-PDP Iron(II) Bis(hexafluoroantimonate); Iron(II) complex with N,N'-bis(2-pyridylmethyl)-2,2'-bipyrrolidine and acetonitrile, hexafluoroantimonate salt; Chiral Iron Pdp Catalyst; Asymmetric Iron Catalyst; [Fe((R,R)-Pdp)(CH₃CN)₂](SbF₆)₂
EINECS	Contact for details

Quality Control

Every batch of our Fe(R,R-Pdp) White-Chen Catalyst is produced and tested under strict quality management systems to ensure exceptional lot-to-lot consistency and catalytic performance. We employ advanced analytical techniques including NMR, HPLC, and elemental analysis to verify identity, chiral purity, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will degrade its catalytic activity.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (ee)	≥ 99.0%
Iron Content	6.5 - 7.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.