Description

Ethanol, 2-[2-[2-[(6-Chlorohexyl)Oxy]Ethoxy]Ethoxy]- is a specialized polyethylene glycol (PEG) derivative featuring a terminal chlorohexyl group, designed as a versatile bifunctional linker for advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture, offering a reactive halogen terminus and a hydrophilic PEG spacer for solubility and biocompatibility. It is primarily utilized in the development of pharmaceutical intermediates, bioconjugates, and functionalized materials for the life sciences and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of prodrugs, targeted drug delivery systems, and antibody-drug conjugates (ADCs).
• Bioconjugation & PEGylation: Used to attach therapeutic molecules (e.g., peptides, proteins) to carriers or surfaces, improving pharmacokinetics and stability.
• Polymer & Material Science: Acts as a functional monomer or cross-linker for creating hydrogels, smart polymers, and surface-modified nanoparticles.
• Diagnostic Reagents: Employed in the fabrication of biosensors, imaging probes, and assay components where a defined spacer arm is required.
• Chemical Biology Research: A valuable tool for probe development, ligand tethering, and studying biomolecular interactions in academic and industrial R&D.
• Surface Functionalization: Used to modify the properties of glass, silicon, or polymer surfaces for specific biological or chemical applications.

Basic Information

Product Name	Ethanol, 2-[2-[2-[(6-Chlorohexyl)Oxy]Ethoxy]Ethoxy]-
CAS No.	1355955-95-1
Molecular Formula	C14H29ClO4
Molecular Weight	308.83 g/mol
Synonyms	6-Chlorohexyl-triethylene glycol; 2-[2-[2-[(6-Chlorohexyl)oxy]ethoxy]ethoxy]ethanol; Triethylene glycol monochlorohexyl ether; Chlorohexyl-PEG3-alcohol; 1-(6-Chlorohexyloxy)-3,6,9-trioxaundecan-11-ol; PEG3-Chlorohexane; 11-Hydroxy-3,6,9-trioxa-1-undecyl chloride
EINECS	Contact for details

Quality Control

Our production of Ethanol, 2-[2-[2-[(6-Chlorohexyl)Oxy]Ethoxy]Ethoxy]- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC for residual solvent analysis, to ensure consistency and reliability for critical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.