Description

1-(Pyridine-2-Sulfonyl)-Piperidin-3-Ylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct sulfonamide-piperidine-pyridine core structure. This compound is valued for its role as a critical building block in the synthesis of novel small-molecule therapeutics, particularly in drug discovery programs targeting enzyme inhibition. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new chemical entities for oncology, neurology, and anti-infective applications. The hydrochloride salt form enhances stability and handling properties for precise synthetic operations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those designed as kinase inhibitors or protease inhibitors.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Biochemical Reagent: Employed as a reference standard or a tool compound in biochemical assays to study specific biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	1-(Pyridine-2-Sulfonyl)-Piperidin-3-Ylamine Hydrochloride
CAS No.	1353986-18-1
Molecular Formula	C11H16ClN3O2S
Molecular Weight	289.78 g/mol
Synonyms	1-(Pyridin-2-ylsulfonyl)piperidin-3-amine hydrochloride; 3-Amino-1-(pyridine-2-sulfonyl)piperidine hydrochloride; 1-(Pyridine-2-sulfonyl)piperidin-3-amine HCl; Piperidin-3-amine, 1-(2-pyridinylsulfonyl)-, hydrochloride; 1-(Pyridin-2-sulfonyl)piperidin-3-aminium chloride; 1353986-18-1 (CAS); 1-(2-Pyridylsulfonyl)-3-aminopiperidine hydrochloride
EINECS	Contact for details

Quality Control

Our production of 1-(Pyridine-2-Sulfonyl)-Piperidin-3-Ylamine Hydrochloride adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from analytical methods including HPLC, NMR, and mass spectrometry. We support compliance with relevant guidelines for advanced intermediates in drug substance development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.