Description

3-(Bromomethyl)-6-Chloropyridazine Hydrochloride is a high-purity, multi-functional halogenated pyridazine building block essential for advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules in pharmaceutical and agrochemical research, offering versatile reactivity for nucleophilic substitution and cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyridazine core for bioactivity.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Serves as a versatile linker or warhead component in the design of targeted protein degradation molecules.
• Material Science Precursor: Employed in the synthesis of functionalized ligands for catalysts or as a monomer for specialized polymers.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce complex pyridazine motifs.
• Academic & Contract Research: A valuable reagent for methodological studies in heterocyclic and medicinal chemistry within university and CRO laboratories.

Basic Information

Item	Detail
Product Name	3-(Bromomethyl)-6-Chloropyridazine Hydrochloride
CAS No.	1353976-37-0
Molecular Formula	C5H5BrCl2N2
Molecular Weight	248.92 g/mol
Synonyms	6-Chloro-3-(bromomethyl)pyridazine Hydrochloride; 3-Bromomethyl-6-chloropyridazine HCl; 6-Chloro-3-(bromomethyl)pyridazine Hydrochloride Salt; (6-Chloropyridazin-3-yl)methyl Bromide Hydrochloride; 3-(Bromomethyl)-6-chloro-1,2-diazine Hydrochloride; 6-Chloro-3-pyridazinemethyl Bromide Hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(Bromomethyl)-6-Chloropyridazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment supports applications requiring high-purity intermediates under ISO and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.