Description

[1-(2-Furan-2-Yl-2-Oxo-Ethyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex synthesis pathways. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for constructing novel molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs) and therapeutic candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule assembly.
• Academic Research: Utilized in university and institutional labs for exploring new heterocyclic chemistry and reaction methodologies.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	[1-(2-Furan-2-Yl-2-Oxo-Ethyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester
CAS No.	1353946-44-7
Molecular Formula	C16H24N2O4
Molecular Weight	308.37 g/mol
Synonyms	tert-Butyl N-[1-(2-furan-2-yl-2-oxoethyl)piperidin-4-yl]carbamate; 1-(2-Furan-2-yl-2-oxo-ethyl)-piperidin-4-yl-carbamic acid tert-butyl ester; BOC-4-Amino-1-(2-furoylmethyl)piperidine; N-Boc-4-amino-1-(2-furoylmethyl)piperidine; 4-[(tert-Butoxycarbonyl)amino]-1-(2-furoylmethyl)piperidine; (1-{2-[(tert-Butoxycarbonyl)amino]ethyl}piperidin-4-yl)(furan-2-yl)methanone (Related structure); BOC-protected furoylmethyl piperidine amine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes. We adhere to cGMP principles where applicable to support our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.