Description

3-Bromo-6-Fluoropyridazine is a high-purity halogenated pyridazine derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional halogen substitution pattern makes it a versatile intermediate for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions, enabling the introduction of the pyridazine moiety into complex molecules.
• Chemical Biology & Proteomics: Utilized as a molecular tag or linker in probe development for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	3-Bromo-6-Fluoropyridazine
CAS No.	1353854-35-9
Molecular Formula	C4H2BrFN2
Molecular Weight	176.97 g/mol
Synonyms	6-Fluoro-3-bromopyridazine; 3-Bromo-6-fluoropyridazine; Fluoropyridazine, 3-bromo-; Pyridazine, 3-bromo-6-fluoro-; 1353854-35-9; 3-Br-6-F-pyridazine
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-6-Fluoropyridazine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for research and commercial synthesis. Our standard quality control includes identity confirmation by spectroscopic methods (NMR, IR, MS) and purity assessment by chromatographic techniques (HPLC, GC). A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.