Description

Imidazo[1,2-B]Pyridazine, 2-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, organoboron building block essential for modern synthetic chemistry. This compound is a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of drug candidates targeting various therapeutic areas, including oncology and CNS disorders.
• Suzuki-Miyaura Cross-Coupling: Enables the formation of carbon-carbon bonds to create complex, functionalized heterocyclic compounds.
• Agrochemical Research: Used in the development of novel pesticides and herbicides with specific biological activity.
• Material Science: Serves as a precursor for organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for biological target validation.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and library synthesis in academic and CRO laboratories.

Basic Information

Product Name	Imidazo[1,2-B]Pyridazine, 2-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1353584-74-3
Molecular Formula	C₁₃H₂₀BN₃O₂
Molecular Weight	261.13 g/mol
Synonyms	2-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-b]pyridazine; 2-Methylimidazo[1,2-b]pyridazine-6-boronic acid pinacol ester; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylimidazo[1,2-b]pyridazine; 2-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-imidazo[1,2-b]pyridazine; Imidazo[1,2-b]pyridazine-6-boronic acid, 2-methyl-, pinacol ester; 1353584-74-3
EINECS	Contact for details

Quality Control

Every batch of Imidazo[1,2-B]Pyridazine, 2-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured and tested under strict quality management systems to ensure high purity, batch-to-batch consistency, and reliable performance in sensitive coupling reactions. Our products undergo rigorous analytical testing, including HPLC, NMR, and LC-MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.