Description

7-(Trifluoromethyl)Phthalazin-1-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its distinct trifluoromethyl-substituted phthalazine core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors and other biologically active compounds.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the phthalazinone scaffold.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Chemical Synthesis: Employed as a versatile building block for introducing the trifluoromethyl group into complex molecular architectures in medicinal and synthetic chemistry.

Basic Information

Product Name	7-(Trifluoromethyl)Phthalazin-1-Ol
CAS No.	1352933-99-3
Molecular Formula	C9H5F3N2O
Molecular Weight	214.15 g/mol
Synonyms	1-Hydroxy-7-(trifluoromethyl)phthalazine; 7-(Trifluoromethyl)-1(2H)-phthalazinone; 7-(Trifluoromethyl)phthalazin-1(2H)-one; 1(2H)-Phthalazinone, 7-(trifluoromethyl)-; 7-Trifluoromethyl-1-phthalazinone; 7-Trifluoromethylphthalazin-1-ol
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)Phthalazin-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.