Description

S-Acetyl-Peg6-Alcohol is a functionalized polyethylene glycol (PEG) derivative featuring a terminal acetyl-protected alcohol group. This compound is a crucial bifunctional linker and building block in advanced organic synthesis and bioconjugation chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for creating prodrugs, modifying biomolecules, and developing novel drug delivery systems.

Application

• Bioconjugation Linker: Used for the site-specific modification of peptides, proteins, and antibodies to enhance solubility, stability, and pharmacokinetic properties.
• Prodrug Synthesis: Serves as a key intermediate in the design and synthesis of prodrugs, where the acetyl group can be cleaved enzymatically to release the active drug moiety.
• Polymer Chemistry: Acts as a versatile monomer or initiator for the synthesis of functionalized PEG-based polymers, hydrogels, and smart materials.
• Drug Delivery Systems: Incorporated into the structure of nanoparticles, liposomes, and micelles to control drug release profiles and target specific tissues.
• Surface Modification: Employed to functionalize surfaces and nanomaterials with hydrophilic PEG chains to reduce non-specific binding and improve biocompatibility.
• Cross-linking Agent: Utilized in the preparation of cross-linked networks for biomedical applications such as tissue engineering scaffolds and controlled-release matrices.

Basic Information

Product Name	S-Acetyl-Peg6-Alcohol
CAS No.	1352221-63-6
Molecular Formula	C18H36O9
Molecular Weight	396.48 g/mol
Synonyms	1-Acetoxy-3,6,9,12,15,18-hexaoxahenicosan-21-ol; 2-[2-[2-[2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl acetate; Acetyl-PEG6-OH; HO-PEG6-OAc; SAA-PEG6-OH; PEG6 Monoacetate; Hexaethylene glycol monoacetate
EINECS	Contact for details

Quality Control

Our S-Acetyl-Peg6-Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Molecular Weight Confirmation (MS)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.