Description

(3S,5R,6R)-3-Allyl-5-(3-Chlorophenyl)-6-(4-Chlorophenyl)-3-Methyltetrahydro-2H-Pyran-2-One CAS NO 1352076-45-9 is a high-purity, stereochemically defined chiral intermediate with significant synthetic utility. This compound is valued for its complex molecular architecture, which serves as a critical building block in advanced organic synthesis. It is primarily sought after by research institutions and pharmaceutical development teams for the creation of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in medicinal chemistry programs.
• Asymmetric Synthesis: Utilized as a sophisticated precursor for constructing complex molecules with high enantiomeric purity.
• Agrochemical Research: Serves as a potential intermediate in the synthesis of novel crop protection agents and pesticides.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for developing new synthetic routes.
• Fine Chemical Production: Used in the manufacture of specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	(3S,5R,6R)-3-Allyl-5-(3-Chlorophenyl)-6-(4-Chlorophenyl)-3-Methyltetrahydro-2H-Pyran-2-One
CAS No.	1352076-45-9
Molecular Formula	C22H22Cl2O2
Molecular Weight	389.32 g/mol
Synonyms	(3S,5R,6R)-3-Allyl-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyltetrahydro-2H-pyran-2-one; 3-Allyl-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyltetrahydro-2H-pyran-2-one (3S,5R,6R)-; Tetrahydro-2H-pyran-2-one, 3-allyl-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-, (3S,5R,6R)-; CAS 1352076-45-9; Chiral Pyranone Intermediate; 1352076-45-9
EINECS	Contact for details

Quality Control

Our (3S,5R,6R)-3-Allyl-5-(3-Chlorophenyl)-6-(4-Chlorophenyl)-3-Methyltetrahydro-2H-Pyran-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.