Description

Potassium 4-(Tetrahydropyranylmethoxy)Methyltrifluoroborate is a high-value organotrifluoroborate salt, a crucial class of reagents in modern synthetic chemistry. It serves as a stable, air- and moisture-tolerant precursor for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex carbon-carbon bonds. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for the introduction of functionalized aryl and heteroaryl groups in active pharmaceutical ingredient (API) development.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling methodologies.
• Material Science: Employed in the creation of organic electronic materials, liquid crystals, and polymers requiring specific aromatic architectures.
• Academic & Industrial R&D: A versatile reagent for methodology development and the synthesis of complex, polyfunctional molecules in laboratory-scale and process chemistry.
• Suzuki-Miyaura Cross-Coupling: Acts as a stable boronic acid surrogate for coupling with a wide range of aryl/vinyl halides or triflates under mild conditions.

Basic Information

Product Name	Potassium 4-(Tetrahydropyranylmethoxy)Methyltrifluoroborate
CAS No.	1350320-55-6
Molecular Formula	C8H15BF3KO2
Molecular Weight	250.11 g/mol
Synonyms	Potassium (4-((Tetrahydro-2H-pyran-2-yloxy)methoxy)phenyl)trifluoroborate; Potassium [4-[(Tetrahydro-2H-pyran-2-yloxy)methoxy]phenyl]trifluoroborate; 4-(THPOM)-Benzenetrifluoroborate Potassium Salt; [4-[(Tetrahydro-2H-pyran-2-yloxy)methoxy]phenyl]trifluoroboronic Acid Potassium Salt; Potassium 4-[(Tetrahydro-2H-pyran-2-yloxy)methoxy]benzenetrifluoroborate
EINECS	Contact for details

Quality Control

Our production of Potassium 4-(Tetrahydropyranylmethoxy)Methyltrifluoroborate adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized by NMR (1H, 13C, 19F, 11B), HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
19F NMR Purity	≥ 95%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.