Description

5-tert-Butoxy-3-Chloropyridazine is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functionalized pyridazine motifs into complex target molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the pyridazine core for bioactivity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts due to its nitrogen-rich heterocyclic structure.
• Material Science Research: Acts as a precursor for the synthesis of functional organic materials, including liquid crystals and electronic chemicals.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional laboratories for methodological studies in heterocyclic chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	5-tert-Butoxy-3-Chloropyridazine
CAS No.	1346698-35-8
Molecular Formula	C8H11ClN2O
Molecular Weight	186.64 g/mol
Synonyms	3-Chloro-5-(tert-butoxy)pyridazine; 5-(tert-Butoxy)-3-chloropyridazine; 3-Chloro-5-tert-butoxypyridazine; tert-Butyl 3-chloro-5-pyridazinyl ether; Pyridazine, 3-chloro-5-(1,1-dimethylethoxy)-; 1346698-35-8
EINECS	Contact for details

Quality Control

Our 5-tert-Butoxy-3-Chloropyridazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.