Description

3-Chloro-5-(2-Fluoroethoxy)Pyridazine is a high-value, halogenated pyridazine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoroethoxy substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, including potential drug candidates and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Serves as a versatile precursor in the design and synthesis of next-generation herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts due to its electron-deficient pyridazine core.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive components, leveraging its halogenated aromatic system.
• Chemical Biology Probes: Acts as a scaffold for creating molecular probes and tags used in biochemical assay development and diagnostic research.
• Custom Synthesis and Contract Manufacturing: A pivotal starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical industry.

Basic Information

Product Name	3-Chloro-5-(2-Fluoroethoxy)Pyridazine
CAS No.	1346691-39-1
Molecular Formula	C6H6ClFN2O
Molecular Weight	176.57 g/mol
Synonyms	3-Chloro-5-(2-fluoroethoxy)pyridazine; 5-(2-Fluoroethoxy)-3-chloropyridazine; Pyridazine, 3-chloro-5-(2-fluoroethoxy)-; 3-Chloro-5-(fluoroethoxy)pyridazine; 1346691-39-1; 3-Chloro-5-(2-fluoroethoxy)-1,2-diazine
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-(2-Fluoroethoxy)Pyridazine is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with the stringent standards required for pharmaceutical and agrochemical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles as measured by advanced techniques like HPLC, GC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.