Description

3-Chloro-5-(2,2,2-trifluoroethoxy)pyridazine is a specialized fluorinated pyridazine derivative, a key building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the trifluoroethoxy and chloro substituents, enabling precise molecular construction. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and insecticides, leveraging the biological activity of the pyridazine core.
• Material Science Research: Serves as a precursor for synthesizing fluorinated liquid crystals or electronic materials where specific dielectric properties are required.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological systems due to its fluorine atoms, which are useful in NMR studies.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Chloro-5-(2,2,2-trifluoroethoxy)pyridazine
CAS No.	1346691-33-5
Molecular Formula	C6H4ClF3N2O
Molecular Weight	212.56 g/mol
Synonyms	3-Chloro-5-(2,2,2-trifluoroethoxy)pyridazine; 5-(2,2,2-Trifluoroethoxy)-3-chloropyridazine; 3-Chloro-5-(2,2,2-trifluoroethoxy)-1,2-diazine; Pyridazine, 3-chloro-5-(2,2,2-trifluoroethoxy)-; 1346691-33-5
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(2,2,2-trifluoroethoxy)pyridazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.