Description

n-(3,4-Dihydro-2H-Pyrano-[2,3-B]Pyridin-6-Yl)Pivalamide is a high-purity pharmaceutical intermediate and research chemical with a complex fused heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. Pharmaceutical R&D laboratories and fine chemical manufacturers need it to develop next-generation drug candidates, leveraging its unique chemical framework.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex fused pyranopyridine derivatives with potential biological activity.
• Research & Development (R&D): Essential for academic and industrial research programs focused on heterocyclic chemistry and new molecular entity discovery.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up and cGMP production of clinical trial materials.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	n-(3,4-Dihydro-2H-Pyrano-[2,3-B]Pyridin-6-Yl)Pivalamide
CAS No.	1346447-04-8
Molecular Formula	C14H18N2O2
Molecular Weight	246.31 g/mol
Synonyms	Pivalamide, N-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-; 2,2-Dimethyl-N-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)propanamide; 6-Pivalamido-3,4-dihydro-2H-pyrano[2,3-b]pyridine; CAS 1346447-04-8; Pyrano[2,3-b]pyridine-6-carboxamide derivative
EINECS	Contact for details

Quality Control

Our n-(3,4-Dihydro-2H-Pyrano-[2,3-B]Pyridin-6-Yl)Pivalamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with full traceability are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.