Description

2H-Pyran-4-Propanoic Acid, α-Aminotetrahydro-, (αs)- is a high-purity chiral intermediate with significant synthetic utility. This compound matters for its role as a key building block in the development of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure agrochemicals, such as herbicides and fungicides, to enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Research: Incorporated into the backbone of peptidomimetics and other bioactive compounds to modulate their pharmacokinetic properties.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers with unique optical or mechanical properties.

Basic Information

Item	Details
Product Name	2H-Pyran-4-Propanoic Acid, α-Aminotetrahydro-, (αs)-
CAS No.	1344910-91-3
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	(αS)-α-Aminotetrahydro-2H-pyran-4-propanoic Acid; (S)-3-(4-Aminotetrahydro-2H-pyran-4-yl)propanoic Acid; (S)-4-(2-Carboxyethyl)-4-aminotetrahydropyran; Tetrahydro-2H-pyran-4-propanoic acid, α-amino-, (αS)-; 4-Aminotetrahydropyran-4-propionic Acid (S-enantiomer); AATP; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 2H-Pyran-4-Propanoic Acid, α-Aminotetrahydro-, (αs)- is produced under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity compliant with cGMP standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.