Description

1-Chloro-3-Ethynyl-2-Methylbenzene is a specialized aromatic building block featuring both chloro and ethynyl substituents. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The ethynyl group is pivotal in Sonogashira and other palladium-catalyzed coupling reactions to form conjugated systems.
• Chemical Derivatization: Used to introduce the ethynyl functionality into larger molecular frameworks for further functionalization.
• Academic & Industrial R&D: A critical reagent for exploratory chemistry in university and corporate research laboratories.

Basic Information

Product Name	1-Chloro-3-Ethynyl-2-Methylbenzene
CAS No.	1342063-35-7
Molecular Formula	C9H7Cl
Molecular Weight	150.60 g/mol
Synonyms	2-Chloro-6-ethynyltoluene; 3-Chloro-2-methylphenylacetylene; 1-Chloro-3-ethynyl-2-methyl-benzene; 2-Methyl-6-ethynylchlorobenzene; 2-Chloro-6-methylphenylacetylene; (3-Chloro-2-methylphenyl)ethyne
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Ethynyl-2-Methylbenzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.