Description

Racemic-(3R,3Ar,7Ar)-tert-Butyl 3-(((Benzyloxy)Carbonyl)Amino)Hexahydropyrano[3,2-B]Pyrrole-1(2H)-Carboxylate is a sophisticated chiral building block and advanced pharmaceutical intermediate. This compound is of significant value for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing new therapeutic agents, especially those targeting central nervous system disorders or requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Asymmetric Synthesis: Serves as a precursor for constructing complex, stereochemically defined fused ring systems common in bioactive molecules.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and heterocyclic chemistry.

Basic Information

Product Name	Racemic-(3R,3Ar,7Ar)-tert-Butyl 3-(((Benzyloxy)Carbonyl)Amino)Hexahydropyrano[3,2-B]Pyrrole-1(2H)-Carboxylate
CAS No.	1341039-68-6
Molecular Formula	C20H28N2O5
Molecular Weight	376.45 g/mol
Synonyms	tert-Butyl 3-(((benzyloxy)carbonyl)amino)hexahydropyrano[3,2-b]pyrrole-1(2H)-carboxylate; (3R,3aR,7aR)-tert-Butyl 3-((((benzyloxy)carbonyl)amino)hexahydro-2H-pyrano[3,2-b]pyrrole-1-carboxylate; 1,2,3,3a,4,7a-Hexahydro-5H-pyrano[3,2-b]pyrrole-5-carboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3R,3aR,7aR)-; (3R,3aR,7aR)-tert-Butyl 3-((((benzyloxy)carbonyl)amino)octahydropyrano[3,2-b]pyrrole-1-carboxylate; Cbz-protected amino pyranopyrrolidine tert-butyl ester; CAS 1341039-68-6
EINECS	Contact for details

Quality Control

Our Racemic-(3R,3Ar,7Ar)-tert-Butyl 3-(((Benzyloxy)Carbonyl)Amino)Hexahydropyrano[3,2-B]Pyrrole-1(2H)-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and cGMP-grade requirements, with specifications tailored to meet the stringent standards of pharmaceutical R&D and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light) and should be handled in a well-ventilated area, avoiding contact with strong acids and organic solvents as indicated by its chemical properties. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.