Description

Racemic-(3S,3Ar,7Ar)-tert-Butyl 3-(((Benzyloxy)Carbonyl)Amino)Hexahydropyrano[3,2-B]Pyrrole-1(2H)-Carboxylate is a sophisticated chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on creating novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral targets.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetic Synthesis: Used in the construction of complex peptidomimetics and constrained amino acid analogs due to its fused pyranopyrrole structure.
• Asymmetric Synthesis: Acts as a starting material or intermediate for the preparation of enantiomerically pure compounds in asymmetric catalysis and synthesis.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential API candidates from milligram to kilogram scale.
• Academic & Institutional Research: Utilized in university and research institute laboratories for methodological development in organic and heterocyclic chemistry.

Basic Information

Product Name	Racemic-(3S,3Ar,7Ar)-tert-Butyl 3-(((Benzyloxy)Carbonyl)Amino)Hexahydropyrano[3,2-B]Pyrrole-1(2H)-Carboxylate
CAS No.	1341038-91-2
Molecular Formula	C20H28N2O5
Molecular Weight	376.45 g/mol
Synonyms	tert-Butyl 3-(((benzyloxy)carbonyl)amino)hexahydropyrano[3,2-b]pyrrole-1(2H)-carboxylate; (3S,3aR,7aR)-tert-Butyl 3-((((benzyloxy)carbonyl)amino)hexahydro-2H-pyrano[3,2-b]pyrrole-1-carboxylate; 1(2H)-Pyranopyrrole-1-carboxylic acid, 3-(((benzyloxy)carbonyl)amino)hexahydro-, 1,1-dimethylethyl ester, (3S,3aR,7aR)-; 1,1-Dimethylethyl (3S,3aR,7aR)-3-[[(phenylmethoxy)carbonyl]amino]hexahydro-2H-pyrano[3,2-b]pyrrole-1-carboxylate; Cbz-protected pyranopyrrolidine tert-butyl ester; CAS 1341038-91-2
EINECS	Contact for details

Quality Control

Our Racemic-(3S,3Ar,7Ar)-tert-Butyl 3-(((Benzyloxy)Carbonyl)Amino)Hexahydropyrano[3,2-B]Pyrrole-1(2H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Specified racemic mixture
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.