Description

5-Hydroxy-3-Methoxy-Naphthalene-2-Carboxylic Acid is a specialized naphthalene derivative that serves as a high-value intermediate in advanced organic synthesis. Its unique substitution pattern makes it a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional dyes. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific hydroxy and methoxy functionalities into naphthalene-based systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and plant growth regulators where the naphthalene core provides specific biological activity.
• Functional Dye & Pigment Manufacturing: Serves as a core structure for producing high-performance dyes, optical brighteners, and pigments due to its conjugated aromatic system.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a starting material for electron-transport or host materials in OLED device fabrication.
• Ligand & Catalyst Development: Utilized in the preparation of chelating ligands for metal catalysts used in asymmetric synthesis and polymerization processes.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry and material science research.

Basic Information

Product Name	5-Hydroxy-3-Methoxy-Naphthalene-2-Carboxylic Acid
CAS No.	1341038-04-7
Molecular Formula	C₁₂H₁₀O₄
Molecular Weight	218.21 g/mol
Synonyms	2-Naphthoic acid, 5-hydroxy-3-methoxy-; 3-Methoxy-5-hydroxynaphthalene-2-carboxylic acid; 5-Hydroxy-3-methoxy-2-naphthoic acid; 5-Hydroxy-3-methoxynaphthalene-2-carboxylic acid; 1341038-04-7; 5-Hydroxy-3-methoxynaphthalene-2-carboxylic acid; 3-Methoxy-5-hydroxy-2-naphthoic acid
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-3-Methoxy-Naphthalene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.