Description

2-(1,1-Dioxidotetrahydro-2H-Thiopyran-3-Yl)Acetic Acid is a high-purity, specialized organic acid derivative featuring a sulfone-substituted thiopyran ring system. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Building block for developing new generation herbicides and fungicides with unique modes of action.
• Ligand & Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Polymer Modification: Functional monomer for introducing polar, sulfone-containing groups into specialty polymers to alter physical properties.
• Material Science: Precursor for advanced organic electronic materials and liquid crystals.
• Chemical Biology Probes: Serves as a core structure for designing activity-based probes and enzyme inhibitors in biochemical research.

Basic Information

Product Name	2-(1,1-Dioxidotetrahydro-2H-Thiopyran-3-Yl)Acetic Acid
CAS No.	1340400-77-2
Molecular Formula	C7H12O4S
Molecular Weight	192.23 g/mol
Synonyms	2-(1,1-Dioxo-1λ⁶-thian-3-yl)acetic acid; 3-Thiopyranacetic acid, tetrahydro-, 1,1-dioxide; Tetrahydro-2H-thiopyran-3-acetic acid, 1,1-dioxide; 2-(1,1-Dioxotetrahydro-2H-thiopyran-3-yl)acetic acid; 2-(Tetrahydro-1,1-dioxido-2H-thiopyran-3-yl)acetic acid; 1340400-77-2; Thiopyran-3-acetic acid derivative
EINECS	Contact for details

Quality Control

Our 2-(1,1-Dioxidotetrahydro-2H-Thiopyran-3-Yl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.