Description

1-(4-Methoxyphenyl)-3-Oxocyclobutanecarboxylic Acid is a high-purity, synthetically versatile organic compound featuring a cyclobutanone core substituted with a carboxylic acid and a 4-methoxyphenyl group. This unique structure makes it a valuable key building block and advanced pharmaceutical intermediate for research and development. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies due to its reactive ketone and carboxylic acid functionalities.
• Agrochemical Research: Serves as a key synthon in the development of new herbicides, fungicides, or plant growth regulators.
• Material Science Research: Potential monomer or cross-linking agent for developing specialized polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Used in university and CRO laboratories for methodological development and exploratory chemical synthesis projects.

Basic Information

Product Name	1-(4-Methoxyphenyl)-3-Oxocyclobutanecarboxylic Acid
CAS No.	1340349-50-9
Molecular Formula	C12H12O4
Molecular Weight	220.22 g/mol
Synonyms	3-Oxo-1-(4-methoxyphenyl)cyclobutanecarboxylic acid; 1-(4-Methoxyphenyl)-3-oxocyclobutane-1-carboxylic acid; 3-Oxo-1-(p-methoxyphenyl)cyclobutanecarboxylic acid; p-Methoxyphenyl 3-oxocyclobutanecarboxylate (related ester form); Cyclobutanecarboxylic acid, 3-oxo-1-(4-methoxyphenyl)-; 1340349-50-9; CAS 1340349-50-9
EINECS	Contact for details

Quality Control

Our production of 1-(4-Methoxyphenyl)-3-Oxocyclobutanecarboxylic Acid adheres to stringent GMP-like guidelines suitable for pharmaceutical R&D. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full spectral data are provided to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.