Description

[1-Allyl-1-(Tetrahydro-2H-Pyran-4-Yl)But-3-En-1-Yl]Amine is a specialized, high-value amine derivative featuring both allyl and tetrahydro-2H-pyran-4-yl functional groups, making it a versatile chiral building block for advanced synthesis. Its unique structure is critical for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific stereochemistry and functional complexity into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its structural motifs can contribute to biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical and Specialty Material Production: Employed in the manufacture of complex, high-value specialty chemicals for electronics and performance materials.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry, exploring new C-N and C-C bond-forming reactions.

Basic Information

Product Name	[1-Allyl-1-(Tetrahydro-2H-Pyran-4-Yl)But-3-En-1-Yl]Amine
CAS No.	1338495-06-9
Molecular Formula	C12H21NO
Molecular Weight	195.30 g/mol
Synonyms	1-Allyl-1-(tetrahydro-2H-pyran-4-yl)but-3-en-1-amine; (1-Allyl-1-(oxan-4-yl)but-3-en-1-yl)amine; 4-(1-Amino-1-allylbut-3-en-1-yl)tetrahydro-2H-pyran; But-3-en-1-amine, 1-allyl-1-(tetrahydro-2H-pyran-4-yl)-; 1338495-06-9; Tertiary amine with allyl and THP groups; Chiral amine building block
EINECS	Contact for details

Quality Control

Our production of [1-Allyl-1-(Tetrahydro-2H-Pyran-4-Yl)But-3-En-1-Yl]Amine adheres to strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and chiral purity assessment, NMR and IR for structural confirmation, and GC for residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or cGMP guidelines for early-phase pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This amine is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizers and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.