Description

1-(3-Chloro-2,6-Difluoro-Phenyl)-Ethylamine is a high-purity, halogenated aromatic amine building block of significant importance in modern synthetic chemistry. Its unique structure, featuring chlorine and fluorine substituents on the phenyl ring, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro and chloro groups can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and functional materials where aromatic amines are required.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry for exploring new synthetic pathways and creating compound libraries.

Basic Information

Product Name	1-(3-Chloro-2,6-Difluoro-Phenyl)-Ethylamine
CAS No.	1337728-56-9
Molecular Formula	C8H8ClF2N
Molecular Weight	191.60 g/mol
Synonyms	1-(3-Chloro-2,6-difluorophenyl)ethan-1-amine; (1-(3-Chloro-2,6-difluorophenyl)ethyl)amine; α-Methyl-3-chloro-2,6-difluorobenzylamine; 3-Chloro-2,6-difluoro-α-methylbenzylamine; 1-(3-Chloro-2,6-difluorophenyl)ethanamine; 1337728-56-9; Benzenemethanamine, 3-chloro-α,2,6-trifluoro- (related); 1-(3-Chloro-2,6-difluoro-phenyl)-ethylamine
EINECS	Contact for details

Quality Control

Our 1-(3-Chloro-2,6-Difluoro-Phenyl)-Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Typical 99.0%)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.