Description

4-(1-Aminoethyl)-3-Bromophenol is a specialized brominated phenolic compound featuring a primary amine functional group, making it a versatile intermediate for advanced synthesis. This unique bifunctional structure is critical for creating complex molecules with tailored properties in high-value research and manufacturing. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery and the development of advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging its halogenated phenolic core.
• Ligand and Catalyst Development: Serves as a precursor for creating chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce amine and phenolic functionalities into polymer backbones, enhancing properties like adhesion, UV stability, and cross-linking potential.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized azo dyes and high-performance pigments where bromine substitution is required for color fastness and specific spectral properties.
• Bioconjugation Chemistry: The amine group enables its use in linking pharmacophores or creating probe molecules for biochemical and diagnostic research.

Basic Information

Product Name	4-(1-Aminoethyl)-3-Bromophenol
CAS No.	1337667-66-9
Molecular Formula	C8H10BrNO
Molecular Weight	216.08 g/mol
Synonyms	3-Bromo-4-(1-aminoethyl)phenol; 1-(3-Bromo-4-hydroxyphenyl)ethan-1-amine; 4-(1-Aminoethyl)-3-bromophenol; 3-Bromo-4-(α-aminoethyl)phenol; (1-(3-Bromo-4-hydroxyphenyl)ethyl)amine; 4-(Aminoethyl)-3-bromophenol; BR-4-AEP
EINECS	Contact for details

Quality Control

Our 4-(1-Aminoethyl)-3-Bromophenol is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and process development. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.