Description

2-(Boc-Amino)-2-(4-tert-Butyl-Phenyl)Acetic Acid is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile chiral intermediate with a tert-butyl-protected amine group, enabling complex peptide coupling and pharmaceutical research. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in peptide-mimetic and small molecule therapeutics.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate protected amino acid residues into complex sequences.
• Agrochemical Research: Serves as a precursor in the development of advanced herbicides, fungicides, and plant growth regulators with specific chiral activity.
• Ligand Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Protecting Group Strategy: The Boc (tert-butoxycarbonyl) group provides orthogonal protection for amines in multi-step synthetic routes.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	2-(Boc-Amino)-2-(4-tert-Butyl-Phenyl)Acetic Acid
CAS No.	1336889-00-9
Molecular Formula	C₁₇H₂₅NO₄
Molecular Weight	307.38 g/mol
Synonyms	Boc-4-tert-butyl-DL-phenylglycine; 2-[(tert-Butoxycarbonyl)amino]-2-[4-(tert-butyl)phenyl]acetic acid; N-Boc-2-amino-2-(4-tert-butylphenyl)acetic acid; N-(tert-Butoxycarbonyl)-4-tert-butylphenylglycine; (4-tert-Butylphenyl)((tert-butoxycarbonyl)amino)acetic acid; 2-(Boc-amino)-2-(p-tert-butylphenyl)acetic acid; N-Boc-α-amino-4-tert-butylphenylacetic acid
EINECS	Contact for details

Quality Control

Our 2-(Boc-Amino)-2-(4-tert-Butyl-Phenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.