Description

2-Azabicyclo[2.2.2]Octan-3-One, 1-(Hydroxymethyl)- is a high-value, advanced pharmaceutical intermediate featuring a unique bridged bicyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering a versatile chiral scaffold. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of novel, high-efficacy pesticides and herbicides with specific stereochemical requirements.
• Asymmetric Catalysis: Serves as a precursor or ligand for chiral catalysts used in stereoselective synthesis.
• Academic & Industrial R&D: A valuable tool compound for medicinal chemistry and process research in both academic and corporate settings.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring a rigid, nitrogen-containing bicyclic framework.

Basic Information

Product Name	2-Azabicyclo[2.2.2]Octan-3-One, 1-(Hydroxymethyl)-
CAS No.	1334412-35-9
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	1-(Hydroxymethyl)-2-azabicyclo[2.2.2]octan-3-one; 2-Azabicyclo[2.2.2]octan-3-one, 1-(hydroxymethyl)-; 1-(Hydroxymethyl)-3-quinuclidinone; 3-Quinuclidinone, 1-(hydroxymethyl)-; (1-Hydroxymethyl)quinuclidin-3-one; Bridged bicyclic lactam intermediate; Hydroxymethyl quinuclidinone
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[2.2.2]Octan-3-One, 1-(Hydroxymethyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.