Description

3-[(E)-(2-Chlorophenyl)Methylidene]-2,3-Dihydro-4H-Chromen-4-One is a high-purity, synthetic organic compound belonging to the chromenone class, characterized by its distinct molecular structure featuring a chlorophenyl substituent. This compound serves as a critical advanced intermediate in the research and development of novel pharmaceuticals and agrochemicals, where precise molecular architecture is paramount. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing target molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting inflammation, CNS disorders, or oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, such as herbicides or fungicides.
• Chemical Synthesis: Serves as a versatile precursor in organic synthesis for constructing complex heterocyclic frameworks in academic and industrial research.
• Material Science: Potential intermediate in the development of specialty chemicals, dyes, or functional organic materials.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-[(E)-(2-Chlorophenyl)Methylidene]-2,3-Dihydro-4H-Chromen-4-One
CAS No.	1333395-36-0
Molecular Formula	C16H11ClO2
Molecular Weight	270.71 g/mol
Synonyms	(E)-3-(2-Chlorobenzylidene)chroman-4-one; 3-[(E)-(2-Chlorobenzylidene)]-2,3-dihydro-4H-chromen-4-one; 2H-1-Benzopyran-4-one, 3-[(E)-[(2-chlorophenyl)methylene]dihydro-; 3-(2-Chlorobenzylidene)-4-chromanone; 4H-Chromen-4-one, 3-[(E)-(2-chlorophenyl)methylene]-2,3-dihydro-; Light-sensitive chromenone derivative
EINECS	Contact for details

Quality Control

Our 3-[(E)-(2-Chlorophenyl)Methylidene]-2,3-Dihydro-4H-Chromen-4-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our commitment to cGMP principles and data integrity ensures a reliable supply for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.