Description

6-(Thiomorpholin-4-Yl)-2,3-Dihydropyridazin-3-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining thiomorpholine and dihydropyridazinone moieties. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel small-molecule drugs.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: Used in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• CNS-Active Compound Synthesis: Employed in creating candidates for neurological and psychiatric disorder treatments.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical R&D.

Basic Information

Product Name	6-(Thiomorpholin-4-Yl)-2,3-Dihydropyridazin-3-One
CAS No.	1332172-25-4
Molecular Formula	C9H13N3OS
Molecular Weight	211.28 g/mol
Synonyms	6-(Thiomorpholin-4-yl)-2,3-dihydropyridazin-3-one; 2,3-Dihydro-6-(4-thiomorpholinyl)pyridazin-3-one; 3-Oxo-6-(thiomorpholin-4-yl)-2,3-dihydropyridazine; 6-(Thiomorpholin-4-yl)-1,2-dihydropyridazin-3-one; 1332172-25-4; Thiomorpholine-pyridazinone derivative
EINECS	Contact for details

Quality Control

Our 6-(Thiomorpholin-4-Yl)-2,3-Dihydropyridazin-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with the standards expected for pharmaceutical R&D, and we can support projects requiring compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.