Description

5-o-Acetyl-4'-o-tert-Butyldimethylsilyl Genistein is a key protected derivative of the isoflavone genistein, specifically designed for advanced synthetic chemistry applications. This compound is critical for researchers and manufacturers requiring precise control over reaction pathways, particularly in the synthesis of complex bioactive molecules. It is primarily utilized in pharmaceutical R&D, fine chemical synthesis, and the development of novel nutraceutical ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel drug candidates, especially those targeting hormone-related pathways.
• Chemical Research & Development: Used in academic and industrial labs to study structure-activity relationships (SAR) and to create new genistein analogs with modified properties.
• Fine Chemical Synthesis: Employed in the production of high-value, specialized compounds where selective deprotection of the acetyl and TBDMS groups is required.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in the production of isoflavone-based products.
• Bioconjugate Chemistry: Facilitates the creation of labeled or tagged genistein derivatives for biochemical and diagnostic applications.

Basic Information

Product Name	5-o-Acetyl-4'-o-tert-Butyldimethylsilyl Genistein
CAS No.	1330249-25-6
Molecular Formula	C25H30O6Si
Molecular Weight	454.60 g/mol
Synonyms	Genistein 5-acetate 4'-TBDMS ether; 4'-O-(tert-Butyldimethylsilyl)-5-O-acetylgenistein; 5-Acetyl-4'-tert-butyldimethylsilylgenistein; 7-Hydroxy-3-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl-5-[(acetyl)oxy]-4H-1-benzopyran-4-one; TBDMS-protected Genistein acetate; 5-O-Acetylgenistein 4'-O-TBDMS ether
EINECS	Contact for details

Quality Control

Our 5-o-Acetyl-4'-o-tert-Butyldimethylsilyl Genistein is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.