Description

(5R)-5-Cyclohexyl-6,7-Dihydro-2-(2,3,4,5,6-Pentafluorophenyl)-5H-Pyrrolo[2,1-C]-1,2,4-Triazolium Tetrafluoroborate is a high-purity, advanced pharmaceutical intermediate and organocatalyst. This compound is valued for its role as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and development chemists and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific stereochemistry and fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated compounds.
• Organocatalyst: Utilized as an asymmetric catalyst or catalyst precursor in enantioselective organic transformations.
• Agrochemical Synthesis: Serves as a building block for developing advanced, fluorinated pesticides and herbicides with enhanced activity.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials with unique electronic properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, especially in fluorination and cyclization reactions.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of fluorinated fine chemicals.

Basic Information

Product Name	(5R)-5-Cyclohexyl-6,7-Dihydro-2-(2,3,4,5,6-Pentafluorophenyl)-5H-Pyrrolo[2,1-C]-1,2,4-Triazolium Tetrafluoroborate
CAS No.	1318249-54-5
Molecular Formula	C18H18BF9N3
Molecular Weight	443.16 g/mol
Synonyms	(5R)-5-Cyclohexyl-2-(perfluorophenyl)-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-4-ium tetrafluoroborate; 5H-Pyrrolo[2,1-c][1,2,4]triazol-4-ium, 5-cyclohexyl-6,7-dihydro-2-(2,3,4,5,6-pentafluorophenyl)-, tetrafluoroborate(1-), (5R)-; (R)-5-Cyclohexyl-2-(pentafluorophenyl)-5,6,7-trihydro-4H-pyrrolo[2,1-c][1,2,4]triazol-4-ium tetrafluoroborate; Fluorinated Pyrrolotriazolium Salt; Chiral Triazolium Salt; Organocatalyst 1318249-54-5.
EINECS	Contact for details

Quality Control

Our (5R)-5-Cyclohexyl-6,7-Dihydro-2-(2,3,4,5,6-Pentafluorophenyl)-5H-Pyrrolo[2,1-C]-1,2,4-Triazolium Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.