Description

n-tert-Butyl-2,3-Difluoro-6-Nitroaniline is a high-purity fluorinated aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both electron-withdrawing nitro and fluorine groups alongside a sterically hindered tert-butyl amine, makes it an invaluable intermediate for creating complex molecules with tailored properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the difluoro and nitro groups contribute to biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments due to its aromatic amine backbone and substituents that influence color and lightfastness.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to construct complex biaryl amine structures.

Basic Information

Product Name	n-tert-Butyl-2,3-Difluoro-6-Nitroaniline
CAS No.	1314985-42-6
Molecular Formula	C10H12F2N2O2
Molecular Weight	230.21 g/mol
Synonyms	2,3-Difluoro-6-nitro-N-(tert-butyl)aniline; 1-(tert-Butylamino)-2,3-difluoro-4-nitrobenzene; N-(tert-Butyl)-2,3-difluoro-6-nitrobenzenamine; 2,3-Difluoro-N-(1,1-dimethylethyl)-6-nitroaniline; 6-Nitro-N-tert-butyl-2,3-difluoroaniline; Benzenamine, 2,3-difluoro-N-(1,1-dimethylethyl)-6-nitro-; N-tert-Butyl-2,3-difluoro-6-nitroaniline
EINECS	Contact for details

Quality Control

Our n-tert-Butyl-2,3-Difluoro-6-Nitroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.