Description

4-Bromopyridazine Hydrochloride is a high-value halogenated heterocyclic building block essential for advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its bromine atom offers a versatile handle for further functionalization via cross-coupling reactions. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, drug discovery, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging the pyridazine core for biological activity.
• Material Science Research: Serves as a building block for creating novel organic ligands, catalysts, and functional polymers with specific electronic properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to create complex biaryl and heteroaryl structures.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and tags for studying biological systems and protein interactions.

Basic Information

Product Name	4-Bromopyridazine Hydrochloride
CAS No.	1314777-62-2
Molecular Formula	C4H4BrClN2
Molecular Weight	195.45 g/mol
Synonyms	4-Bromopyridazine HCl; 4-Bromopyridazine Hydrochloride Salt; Pyridazine, 4-bromo-, hydrochloride; 4-Bromo-1,2-diazine hydrochloride; 4-Bromopyridazinium chloride
EINECS	Contact for details

Quality Control

Our 4-Bromopyridazine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and NMR for structural confirmation, to meet the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.