Description

3-Chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine hydrochloride is a high-purity, heterocyclic organic compound with a fused bicyclic structure, serving as a critical advanced pharmaceutical intermediate. Its molecular architecture makes it a valuable building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas such as central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially for CNS-targeting therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in the multi-step synthesis of complex active pharmaceutical ingredients (APIs) requiring its specific fused pyridazine-pyridine core.
• Chemical Biology Probes: Serves as a starting material for creating specialized molecular probes to study biological pathways and enzyme functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Used in university and institutional laboratories for fundamental studies in heterocyclic chemistry and new synthetic methodology development.

Basic Information

Product Name	3-Chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine hydrochloride
CAS No.	1314770-27-8
Molecular Formula	C7H9Cl2N3
Molecular Weight	206.07 g/mol
Synonyms	3-Chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine HCl; 3-Chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine monohydrochloride; 5,6,7,8-Tetrahydropyrido[4,3-c]pyridazine, 3-chloro-, hydrochloride; 3-Chloro-5,6,7,8-tetrahydro-4H-pyrido[4,3-c]pyridazine hydrochloride; 1314770-27-8; Pyrido[4,3-c]pyridazine, 3-chloro-5,6,7,8-tetrahydro-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 3-Chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.