Description

2-((tert-Butyldiphenylsilyl)Oxy)Ethyl Trifluoromethanesulfonate is a high-value, protected alcohol-derived triflate reagent, specifically engineered for advanced organic synthesis. This compound matters because it serves as a crucial electrophilic building block for the selective introduction of functionalized ethyl moieties under mild conditions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the alkylation of nucleophiles in the construction of active pharmaceutical ingredients (APIs).
• Nucleoside & Nucleotide Chemistry: Used in the protection and functionalization of sugar alcohols for antiviral and anticancer drug candidates.
• Polymer Science: Acts as a monomer or chain-transfer agent in the synthesis of specialized polymers with tailored properties.
• Material Science: Employed in surface modification and the creation of functional organic-inorganic hybrid materials.
• Agrochemical Development: Utilized in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Cross-Coupling Reactions: Serves as an electrophilic partner in palladium-catalyzed reactions like the Heck, Stille, or Suzuki couplings.
• Ligand and Catalyst Design: Facilitates the introduction of silyl-protected alcohol handles onto complex ligand frameworks.

Basic Information

Product Name	2-((tert-Butyldiphenylsilyl)Oxy)Ethyl Trifluoromethanesulfonate
CAS No.	1314705-19-5
Molecular Formula	C19H23F3O4SSi
Molecular Weight	432.53 g/mol
Synonyms	2-[(tert-Butyldiphenylsilyl)oxy]ethyl Triflate; 2-(tert-Butyldiphenylsiloxy)ethyl Trifluoromethanesulfonate; 2-TBDPSO-ethyl Triflate; Ethanol, 2-[(1,1-dimethylethyl)diphenylsilyl]oxy-, 1-trifluoromethanesulfonate; 2-[(tert-Butyldiphenylsilyl)oxy]ethyl Trifluoromethanesulfonate; TBDPS-protected Ethanol Triflate; 2-Hydroxyethyl TBDPS Ether Triflate
EINECS	Contact for details

Quality Control

Every batch of 2-((tert-Butyldiphenylsilyl)Oxy)Ethyl Trifluoromethanesulfonate is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.