Description

(E)-tert-Butyl 2-(Hydroxyimino)-3-Oxobutanoate CAS NO 1312786-80-3 is a high-purity, specialized organic intermediate characterized by its oxobutanoate and hydroxyimino functional groups. This compound is critical for synthetic chemists requiring precise building blocks for complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research and development teams, as well as production units, within the pharmaceutical, agrochemical, and advanced material science industries.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex heterocycles and target molecules for drug discovery and development programs.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, including herbicides and fungicides.
• Chemical Research: Serves as a versatile reagent in academic and industrial laboratories for method development and novel compound synthesis.
• Peptide Mimetics: Employed in the construction of peptidomimetics and other bioactive compounds due to its reactive carbonyl and imino groups.
• Material Science Precursor: Acts as a precursor for specialty polymers and functional organic materials.

Basic Information

Product Name	(E)-tert-Butyl 2-(Hydroxyimino)-3-Oxobutanoate
CAS No.	1312786-80-3
Molecular Formula	C8H13NO4
Molecular Weight	187.19 g/mol
Synonyms	tert-Butyl 2-(hydroxyimino)-3-oxobutanoate; 3-Oxobutan-2-one O-tert-butyl oxime; 2-(Hydroxyimino)-3-oxobutanoic acid tert-butyl ester; (E)-tert-Butyl acetoacetate oxime; Acetoacetic acid tert-butyl ester oxime; tert-Butyl acetoacetate O-methyloxime (common misnomer); TBHAO; O-tert-Butyl acetoacetoxime
EINECS	Contact for details

Quality Control

Every batch of (E)-tert-Butyl 2-(Hydroxyimino)-3-Oxobutanoate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure compliance with stringent purity specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) and handle it in a moisture-controlled environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.