Description

3-(5-Bromo-Indazol-1-Yl)-Propionic Acid CAS NO 1312138-74-1 is a high-purity, advanced pharmaceutical intermediate featuring a brominated indazole scaffold linked to a propionic acid moiety. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Employed in the development of chemical probes for studying biological pathways and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and bioorganic research projects.

Basic Information

Product Name	3-(5-Bromo-Indazol-1-Yl)-Propionic Acid
CAS No.	1312138-74-1
Molecular Formula	C₁₂H₁₁BrN₂O₂
Molecular Weight	295.13 g/mol
Synonyms	3-(5-Bromo-1H-indazol-1-yl)propanoic acid; 5-Bromo-1-(2-carboxyethyl)-1H-indazole; 1H-Indazole-1-propanoic acid, 5-bromo-; Propionic acid, 3-(5-bromo-1H-indazol-1-yl)-; 1312138-74-1; 3-(5-Bromoindazol-1-yl)propionic Acid
EINECS	Contact for details

Quality Control

Our 3-(5-Bromo-Indazol-1-Yl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) that include data from HPLC, NMR, and mass spectrometry. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.