Description

4-Bromo-2-Chloro-1-Ethylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and process chemists in fine chemical, pharmaceutical R&D, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring specific halogen-substituted phenyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the ethylbenzene core provides specific biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring new reaction methodologies and constructing complex organic molecules.
• Ligand and Catalyst Development: Used to synthesize novel phosphine or nitrogen-based ligands for asymmetric catalysis and metal-organic frameworks.

Basic Information

Product Name	4-Bromo-2-Chloro-1-Ethylbenzene
CAS No.	1310948-67-4
Molecular Formula	C8H8BrCl
Molecular Weight	219.51 g/mol
Synonyms	1-Bromo-4-chloro-2-ethylbenzene; 2-Chloro-4-bromoethylbenzene; 4-Bromo-2-chloroethylbenzene; (4-Bromo-2-chlorophenyl)ethane; 1-Ethyl-4-bromo-2-chlorobenzene; 2-Chloro-1-ethyl-4-bromobenzene; Ethyl-4-bromo-2-chlorobenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-1-Ethylbenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support custom synthesis and can tailor purity grades to meet specific project requirements, from research to cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. The compound is soluble in common organic solvents; ensure containers are kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.