Description

S-(3,3-Difluorocyclobutyl)Ethanethioic Acid Ester is a high-purity, specialized organofluorine building block of significant interest in advanced chemical synthesis. Its unique difluorocyclobutyl thioester structure makes it a valuable intermediate for introducing fluorinated motifs, which are critical for modulating the physicochemical properties of target molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the difluorocyclobutyl group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for synthesizing fluorinated polymers or liquid crystals with tailored thermal and optical properties.
• Fluorine Chemistry: An essential reagent for exploring new fluorination methodologies and creating complex fluorinated molecular architectures in academic and industrial R&D settings.
• Proteomics & Bioconjugation: Potential use as a reactive handle for labeling proteins or other biomolecules, leveraging the thioester functionality for selective conjugation.

Basic Information

Product Name	S-(3,3-Difluorocyclobutyl)Ethanethioic Acid Ester
CAS No.	1310729-92-0
Molecular Formula	C8H10F2OS
Molecular Weight	192.22 g/mol
Synonyms	S-(3,3-Difluorocyclobutyl) ethanethioate; Thioacetic acid S-(3,3-difluorocyclobutyl) ester; 3,3-Difluorocyclobutyl thioacetate; Ethanethioic acid, S-(3,3-difluorocyclobutyl) ester; CAS 1310729-92-0; Difluorocyclobutyl thioacetate
EINECS	Contact for details

Quality Control

Our S-(3,3-Difluorocyclobutyl)Ethanethioic Acid Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including NMR, HPLC, and GC-MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.