Description

6-(1,3-Dioxolan-2-Yl)Pyridine-3-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative crucial for modern synthetic chemistry. This compound serves as a versatile and stable building block, enabling efficient cross-coupling reactions to construct complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides by constructing complex heterocyclic systems.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) and components for organic light-emitting diodes (OLEDs).
• Chemical Biology: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and labeled compounds.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel bidentate ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis projects requiring the introduction of a pyridine moiety with a protected functional group.

Basic Information

Product Name	6-(1,3-Dioxolan-2-Yl)Pyridine-3-Boronic Acid Pinacol Ester
CAS No.	1309982-39-5
Molecular Formula	C14H18BNO4
Molecular Weight	275.11 g/mol
Synonyms	2-[6-(1,3-Dioxolan-2-yl)pyridin-3-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-(1,3-Dioxolan-2-yl)pyridine-3-boronic acid pinacol ester; 3-Pyridineboronic acid, 6-(1,3-dioxolan-2-yl)-, 1,1-dimethylethyl ester; 6-(1,3-Dioxolan-2-yl)-3-pyridinylboronic acid pinacol ester; Pinacol 6-(1,3-dioxolan-2-yl)pyridin-3-ylboronate
EINECS	Contact for details

Quality Control

Our 6-(1,3-Dioxolan-2-Yl)Pyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.