Description

3-Carbethoxy-2,6-Bis(Difluoromethyl)-4H-Pyran-4-One is a specialized fluorinated pyranone derivative, a high-value building block in advanced organic synthesis. Its core value lies in the strategic incorporation of difluoromethyl and carbethoxy functional groups, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the difluoromethyl group enhances lipophilicity and bioavailability.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and advanced materials with unique optical or electronic properties.
• Fluorine Chemistry: An important reagent for introducing fluorine-containing motifs into complex molecular architectures, a crucial strategy in modern medicinal chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	3-Carbethoxy-2,6-Bis(Difluoromethyl)-4H-Pyran-4-One
CAS No.	1309602-66-1
Molecular Formula	C11H10F4O4
Molecular Weight	282.19 g/mol
Synonyms	Ethyl 2,6-bis(difluoromethyl)-4-oxo-4H-pyran-3-carboxylate; 3-Ethoxycarbonyl-2,6-bis(difluoromethyl)-4H-pyran-4-one; 2,6-Bis(difluoromethyl)-4-oxo-4H-pyran-3-carboxylic acid ethyl ester; 4H-Pyran-4-one, 3-(ethoxycarbonyl)-2,6-bis(difluoromethyl)-; 1309602-66-1; 3-Carbethoxy-2,6-difluoromethyl-4H-pyran-4-one
EINECS	Contact for details

Quality Control

Our 3-Carbethoxy-2,6-Bis(Difluoromethyl)-4H-Pyran-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.