Description

(3S,4R)-4-Aminotetrahydro-2H-Pyran-3-Ol is a high-purity chiral amino alcohol building block of significant interest in advanced organic synthesis. Its defined stereochemistry and functional group arrangement make it a valuable intermediate for constructing complex, biologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, antibacterial, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for activity and environmental safety.
• Catalyst Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis, such as hydrogenation or oxidation reactions.
• Peptidomimetics & Scaffold Development: Incorporated into the backbone of peptidomimetics and other molecular scaffolds to modulate pharmacokinetic properties and biological activity.
• Academic & Process Chemistry: Employed in methodological research and scale-up process development for stereoselective synthesis routes.

Basic Information

Product Name	(3S,4R)-4-Aminotetrahydro-2H-Pyran-3-Ol
CAS No.	1309081-53-5
Molecular Formula	C5H11NO2
Molecular Weight	117.15 g/mol
Synonyms	(3S,4R)-4-Aminooxan-3-ol; 4-Aminotetrahydro-2H-pyran-3-ol, (3S,4R)-; (3S,4R)-4-Amino-3-hydroxytetrahydropyran; 3-Pyranol, 4-amino-tetrahydro-, (3S,4R)-; cis-4-Amino-3-hydroxytetrahydropyran; Tetrahydro-2H-pyran-3-ol, 4-amino-, (3S,4R)-
EINECS	Contact for details

Quality Control

Our (3S,4R)-4-Aminotetrahydro-2H-Pyran-3-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), enantiomeric excess, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, and custom synthesis and purification to meet specific client specifications is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.