Description

trans-3-Aminotetrahydro-2H-Pyran-4-Ol CAS NO 1309081-45-5 is a chiral amino alcohol derivative of tetrahydropyran, serving as a valuable and versatile building block in advanced organic synthesis. Its unique stereochemistry and bifunctional nature make it a critical intermediate for constructing complex molecular architectures with high precision. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, including protease inhibitors, neurological agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce enantioselectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where precise molecular structure is essential.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	trans-3-Aminotetrahydro-2H-Pyran-4-Ol
CAS No.	1309081-45-5
Molecular Formula	C5H11NO2
Molecular Weight	117.15 g/mol
Synonyms	trans-3-Amino-4-hydroxytetrahydro-2H-pyran; (3R,4S)-3-Amino-4-hydroxytetrahydro-2H-pyran; (3S,4R)-3-Amino-4-hydroxytetrahydro-2H-pyran; 3-Amino-4-hydroxytetrahydropyran; 4-Hydroxy-3-aminotetrahydropyran; THP Amino Alcohol; 3-Amino-4-hydroxy-tetrahydropyran; 1309081-45-5
EINECS	Contact for details

Quality Control

Our trans-3-Aminotetrahydro-2H-Pyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.