Description

2-(Dimethoxymethyl)-N'-Hydroxybenzenecarboximidamide is a specialized organic compound belonging to the class of amidoxime derivatives, serving as a critical synthetic intermediate and building block. Its molecular structure, featuring both a dimethoxymethyl protecting group and a reactive amidoxime moiety, makes it a versatile precursor for constructing complex heterocycles and functionalized molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those containing nitrogen heterocycles like oxadiazoles, triazoles, and isoxazoles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive functional groups to create novel bioactive structures.
• Chemical Synthesis Reagent: Acts as a versatile precursor for introducing the amidoxime functional group into more complex molecules via condensation or cyclization reactions.
• Material Science: Potential monomer or cross-linking agent in the research of specialty polymers and functional materials.
• Academic & R&D: A valuable tool for methodological studies in organic synthesis and medicinal chemistry within university and corporate research laboratories.

Basic Information

Product Name	2-(Dimethoxymethyl)-N'-Hydroxybenzenecarboximidamide
CAS No.	1306753-75-2
Molecular Formula	C10H14N2O3
Molecular Weight	210.23 g/mol
Synonyms	N'-Hydroxy-2-(dimethoxymethyl)benzenecarboximidamide; Benzenecarboximidamide, N-hydroxy-2-(dimethoxymethyl)-; 2-(Dimethoxymethyl)benzamidoxime; Amidoxime Derivative CAS 1306753-75-2
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of 2-(Dimethoxymethyl)-N'-Hydroxybenzenecarboximidamide is analyzed to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing specifications such as assay (by HPLC), identity confirmation (by IR and/or NMR), and impurity profiles. Our quality system is designed to support cGMP and ISO standards for reliable sourcing in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.