Description

2,3-Dihydro-1H-Isoindole-5-Sulfonic Acid Amide is a high-purity, specialized heterocyclic sulfonamide building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, dyes, and photoactive materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors or receptor modulators.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	2,3-Dihydro-1H-Isoindole-5-Sulfonic Acid Amide
CAS No.	1306603-24-6
Molecular Formula	C8H10N2O2S
Molecular Weight	198.24 g/mol
Synonyms	5-Sulfamoyl-2,3-dihydro-1H-isoindole; 2,3-Dihydro-1H-isoindole-5-sulfonamide; Isoindoline-5-sulfonamide; 1H-Isoindole-5-sulfonic acid amide, 2,3-dihydro-; 5-Aminosulfonyl-2,3-dihydro-1H-isoindole; 2,3-Dihydroisoindole-5-sulfonamide; 5-Sulfonamidoisoindoline
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1H-Isoindole-5-Sulfonic Acid Amide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.