Description

5-Bromo-n-(Quinuclidin-3-Yl)Pyridine-3-Sulfonamide is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1304451-98-6. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the research and development of new drug candidates, particularly for neurological targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for molecules targeting G-protein-coupled receptors (GPCRs).
• Chemical Biology Probes: Serves as a scaffold for developing selective enzyme inhibitors or receptor modulators for biological pathway analysis.
• Process Chemistry: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) during clinical trial material production.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	5-Bromo-n-(Quinuclidin-3-Yl)Pyridine-3-Sulfonamide
CAS No.	1304451-98-6
Molecular Formula	C12H16BrN3O2S
Molecular Weight	346.25 g/mol
Synonyms	5-Bromo-N-(quinuclidin-3-yl)pyridine-3-sulfonamide; 3-Pyridinesulfonamide, 5-bromo-N-3-quinuclidinyl-; 1304451-98-6; 5-Bromo-N-(3-quinuclidinyl)-3-pyridinesulfonamide; 5-Bromo-N-(quinuclidin-3-yl)pyridine-3-sulfonamide; 5-Bromo-N-(3-quinuclidinyl)nicotinic acid sulfonamide; Quinuclidin-3-yl-(5-bromopyridin-3-yl)sulfonamide
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-(Quinuclidin-3-Yl)Pyridine-3-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.