Description

3-Bromo-6-(1-Hydroxy-1-Methylethyl)Pyridazine is a high-purity, functionalized pyridazine derivative serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a tertiary alcohol group, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection research.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of new herbicides, fungicides, and insecticides, leveraging the pyridazine core's bioactivity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and materials science due to its modifiable bromine and hydroxyl sites.
• Chemical Biology Probes: Employed in the development of molecular probes and tags for studying biological processes and target engagement.
• Material Science: Potential monomer or functional additive in the synthesis of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.

Basic Information

Product Name	3-Bromo-6-(1-Hydroxy-1-Methylethyl)Pyridazine
CAS No.	1303968-01-5
Molecular Formula	C7H9BrN2O
Molecular Weight	217.06 g/mol
Synonyms	6-(2-Hydroxypropan-2-yl)-3-bromopyridazine; 3-Bromo-6-(2-hydroxy-2-propyl)pyridazine; 2-(3-Bromopyridazin-6-yl)propan-2-ol; 3-Bromo-6-(1-hydroxy-1-methylethyl)-pyridazine; 3-Bromo-6-(2-hydroxypropan-2-yl)pyridazine; 3-Bromo-6-(α-hydroxyisopropyl)pyridazine
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-6-(1-Hydroxy-1-Methylethyl)Pyridazine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.