Description

5-Bromo-4-Iodo-1,3-Benzodioxole is a halogenated benzodioxole derivative, a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring both bromine and iodine substituents on the aromatic ring, makes it a critical intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for structure-activity relationship (SAR) studies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where halogen atoms tune electronic properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of both bromine and iodine, offering selective reactivity.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and mechanisms.

Basic Information

Item	Details
Product Name	5-Bromo-4-Iodo-1,3-Benzodioxole
CAS No.	1300118-10-8
Molecular Formula	C7H4BrIO2
Molecular Weight	326.92 g/mol
Synonyms	4-Iodo-5-bromo-1,3-benzodioxole; 5-Bromo-4-iodobenzodioxole; 1,3-Benzodioxole, 5-bromo-4-iodo-; 5-Bromo-4-iodo-1,3-benzodioxole; 4-Bromo-5-iodo-1,3-benzodioxole (isomer check); Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Iodo-1,3-Benzodioxole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment supports applications in GMP and research environments where material integrity is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.