Description

1H-Indole-1-Acetic Acid, 3-[[1-[(2,4-Difluorophenyl)Methyl]-1,6-Dihydro-6-Oxo-3-Pyridazinyl]Methyl]-5-Fluoro-2-Methyl- is a high-purity, complex heterocyclic compound designed for advanced research and development applications. This molecule is of significant interest in pharmaceutical discovery due to its intricate structure combining indole and pyridazine moieties with strategic fluorine substitutions. It serves as a critical building block or intermediate for medicinal chemists working on novel therapeutic agents. Target users include R&D laboratories and fine chemical manufacturers in the global life sciences sector.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology, neurology, and anti-infective drug discovery.
• Medicinal Chemistry Research: Used as a core scaffold or derivatization point for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties.
• Biochemical Tool Compound: Employed in vitro and in vivo to probe specific biological pathways and enzyme targets, aiding in the understanding of disease mechanisms.
• Fine Chemical Synthesis: Serves as a specialized intermediate for the custom synthesis of complex molecules for contract research organizations (CROs) and contract development and manufacturing organizations (CDMOs).
• Agrochemical Research: Potential application as an intermediate in the development of new generation crop protection agents with novel modes of action.

Basic Information

Product Name	1H-Indole-1-Acetic Acid, 3-[[1-[(2,4-Difluorophenyl)Methyl]-1,6-Dihydro-6-Oxo-3-Pyridazinyl]Methyl]-5-Fluoro-2-Methyl-
CAS No.	1297276-84-6
Molecular Formula	C23H18F3N3O3
Molecular Weight	441.40 g/mol
Synonyms	3-[[1-[(2,4-Difluorophenyl)methyl]-6-oxo-1,6-dihydropyridazin-3-yl]methyl]-5-fluoro-2-methyl-1H-indole-1-acetic acid; 1H-Indole-1-acetic acid, 3-[[1-[(2,4-difluorophenyl)methyl]-1,6-dihydro-6-oxo-3-pyridazinyl]methyl]-5-fluoro-2-methyl-; 1297276-84-6; 3-({1-[(2,4-Difluorobenzyl)]-6-oxo-1,6-dihydro-3-pyridazinyl}methyl)-5-fluoro-2-methyl-1H-indole-1-acetic Acid
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-1-Acetic Acid, 3-[[1-[(2,4-Difluorophenyl)Methyl]-1,6-Dihydro-6-Oxo-3-Pyridazinyl]Methyl]-5-Fluoro-2-Methyl- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality systems are designed to support cGMP and ISO standards for research-grade fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.