Description

T-Boc-n-Amido-Peg7-Tos CAS NO 1292268-14-4 is a high-purity, heterobifunctional polyethylene glycol (PEG) derivative featuring a tert-butyloxycarbonyl (BOC) protected amine group and a tosylate (Tos) leaving group. This compound is a critical building block for the synthesis of complex bioconjugates and drug delivery systems, enabling precise and controlled chemical linkages. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for developing advanced therapeutics and diagnostic agents.

Application

• Bioconjugation and Linker Chemistry: Acts as a versatile spacer and linker for attaching peptides, proteins, or drug molecules to surfaces, nanoparticles, or other biomolecules.
• PEGylation Reagent: Used to introduce PEG chains onto active molecules to improve solubility, reduce immunogenicity, and enhance circulation time in vivo.
• Prodrug Synthesis: Serves as a key intermediate in the design and synthesis of prodrugs with controlled release profiles.
• Polymer Chemistry: Employed as a functional monomer or cross-linking agent in the synthesis of specialized polymers and hydrogels for biomedical applications.
• Diagnostic Agent Development: Facilitates the creation of labeled probes and contrast agents for imaging and diagnostic assays.
• ADC (Antibody-Drug Conjugate) Development: Provides a functional handle for constructing the linker-payload component of next-generation ADCs.

Basic Information

Product Name	T-Boc-n-Amido-Peg7-Tos
CAS No.	1292268-14-4
Molecular Formula	C33H57NO13S
Molecular Weight	707.87 g/mol
Synonyms	1-Boc-1,8-diamino-3,6-dioxaoctane 8-Tosylate; tert-Butyl (8-((4-methylphenyl)sulfonyl)oxy)-3,6,9,12,15,18,21-heptaoxa-2-azadocosan-22-yl)carbamate; BOC-NH-PEG7-OTs; BOC-Amine-PEG7-Tosylate; 2,5,8,11,14,17,20-Heptaoxadocosan-22-amine, 1-[(1,1-dimethylethoxy)carbonyl]-23-[(4-methylphenyl)sulfonyl]oxy]-; BOC-N-amido-PEG7-OTs; Heterobifunctional PEG derivative BOC-PEG7-OTs; BOC-PEG7-Tos
EINECS	Contact for details

Quality Control

Our T-Boc-n-Amido-Peg7-Tos is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot. We adhere to cGMP principles where applicable to support our customers' development and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.